Deletion of voltage-gated calcium channels in astrocytes decreases neuroinflammation and demyelination in a murine model of multiple sclerosis

The experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis was used in combination with a Cav1.2 conditional knock-out mouse (Cav1.2(KO)) to study the role of astrocytic voltage-gated Ca(++) channels in autoimmune CNS inflammation and demyelination. Cav1.2 channels were specific...

Descripción completa

Detalles Bibliográficos
Autores principales: Denaroso, G. E., Smith, Z., Angeliu, C. G., Cheli, V. T., Wang, C., Paez, P. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644533/
https://www.ncbi.nlm.nih.gov/pubmed/37964385
http://dx.doi.org/10.1186/s12974-023-02948-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644533/
https://www.ncbi.nlm.nih.gov/pubmed/37964385
http://dx.doi.org/10.1186/s12974-023-02948-x

Ejemplares similares