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Deletion of voltage-gated calcium channels in astrocytes decreases neuroinflammation and demyelination in a murine model of multiple sclerosis

The experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis was used in combination with a Cav1.2 conditional knock-out mouse (Cav1.2(KO)) to study the role of astrocytic voltage-gated Ca(++) channels in autoimmune CNS inflammation and demyelination. Cav1.2 channels were specific...

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Detalles Bibliográficos
Autores principales:	Denaroso, G. E., Smith, Z., Angeliu, C. G., Cheli, V. T., Wang, C., Paez, P. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644533/ https://www.ncbi.nlm.nih.gov/pubmed/37964385 http://dx.doi.org/10.1186/s12974-023-02948-x

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