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Inhibition of PKA/CREB1 pathway confers sensitivity to ferroptosis in non-small cell lung cancer

Ferroptosis is a type of regulated cell death characterized by iron accumulation and lipid peroxidation. The molecular mechanisms underlying ferroptosis regulation in non-small cell lung cancer (NSCLC) are poorly understood. In this study, we found that protein kinase A (PKA) inhibition enhanced fer...

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Detalles Bibliográficos
Autores principales: Shan, Guangyao, Bi, Guoshu, Zhao, Guangyin, Liang, Jiaqi, Bian, Yunyi, Zhang, Huan, Jin, Xing, Hu, Zhengyang, Yao, Guangyu, Fan, Hong, Zhan, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644539/
https://www.ncbi.nlm.nih.gov/pubmed/37957645
http://dx.doi.org/10.1186/s12931-023-02567-3