APOE genotype and sex modulate Alzheimer’s disease pathology in aged EFAD transgenic mice

Increasing evidence supports that age, APOE and sex interact to modulate Alzheimer’s disease (AD) risk, however the underlying pathways are unclear. One way that AD risk factors may modulate cognition is by impacting amyloid beta (Aβ) accumulation as plaques, and/or neuroinflammation Therefore, the...

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Detalles Bibliográficos
Autores principales: Balu, Deebika, Valencia-Olvera, Ana C., Islam, Zarak, Mielczarek, Clare, Hansen, Allison, Perez Ramos, Tamara M., York, Jason, LaDu, Mary Jo, Tai, Leon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644540/
https://www.ncbi.nlm.nih.gov/pubmed/38020764
http://dx.doi.org/10.3389/fnagi.2023.1279343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644540/
https://www.ncbi.nlm.nih.gov/pubmed/38020764
http://dx.doi.org/10.3389/fnagi.2023.1279343

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