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Biomineralized tetramethylpyrazine-loaded PCL/gelatin nanofibrous membrane promotes vascularization and bone regeneration of rat cranium defects

Conventional electrospinning produces nanofibers with smooth surfaces that limit biomineralization ability. To overcome this disadvantage, we fabricated a tetramethylpyrazine (TMP)-loaded matrix-mimicking biomineralization in PCL/Gelatin composite electrospun membranes with bubble-shaped nanofibrous...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoyu, Ni, Su, Dai, Ting, Li, Jingyan, Shao, Fang, Liu, Chun, Wang, Jiafeng, Fan, Shijie, Tan, Yadong, Zhang, Linxiang, Jiang, Qiting, Zhao, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644548/
https://www.ncbi.nlm.nih.gov/pubmed/37964381
http://dx.doi.org/10.1186/s12951-023-02155-z