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Network pharmacology and experimental validation methods to reveal the active compounds and hub targets of Curculigo orchioides Gaertn in rheumatoid arthritis

BACKGROUND: Rheumatoid arthritis (RA) is an autoimmune disease that can lead to joint destruction and deformity. Curculigo orchioides Gaertn (CO) was previously revealed to play a significant role in RA treatment. However, the main active ingredients and molecular mechanisms of CO in regulating RA a...

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Detalles Bibliográficos
Autores principales: Liu, Xia, Huang, Mingchun, Wang, Lijuan, Li, Jie, Wu, Weihui, Wang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644664/
https://www.ncbi.nlm.nih.gov/pubmed/37957674
http://dx.doi.org/10.1186/s13018-023-04352-w