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Targeted IFNγ induction by a genetically engineered Salmonella typhimurium is the key to the liver metastasis inhibition in a mouse model of pancreatic neuroendocrine tumor

BACKGROUND: Liver metastasis is one of the primary causes of death for the patients with pancreatic neuroendocrine tumors (PNETs). However, no curative therapy has been developed so far. METHODS: The anti-tumor efficacy of a genetically engineered tumor-targeting Salmonella typhimurium YB1 was evalu...

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Detalles Bibliográficos
Autores principales: Hua, Zhan, Wu, Shan, Zhang, Yulian, Wang, Xiuhong, Cui, Ju, Li, Yunxuan, Yang, Chengcheng, Zhai, Min, Deng, Bo, Yu, Bin, Huang, Jian-Dong, Wang, Zai, Zhou, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644712/
https://www.ncbi.nlm.nih.gov/pubmed/38020179
http://dx.doi.org/10.3389/fmed.2023.1284120