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Targeted IFNγ induction by a genetically engineered Salmonella typhimurium is the key to the liver metastasis inhibition in a mouse model of pancreatic neuroendocrine tumor
BACKGROUND: Liver metastasis is one of the primary causes of death for the patients with pancreatic neuroendocrine tumors (PNETs). However, no curative therapy has been developed so far. METHODS: The anti-tumor efficacy of a genetically engineered tumor-targeting Salmonella typhimurium YB1 was evalu...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644712/ https://www.ncbi.nlm.nih.gov/pubmed/38020179 http://dx.doi.org/10.3389/fmed.2023.1284120 |