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Cabozantinib in neuroendocrine tumors: tackling drug activity and resistance mechanisms

Neuroendocrine tumors (NETs) are highly vascularized malignancies in which angiogenesis may entail cell proliferation and survival. Among the emerging compounds with antivascular properties, cabozantinib (CAB) appeared promising. We analyzed the antitumor activity of CAB against NETs utilizing in vi...

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Detalles Bibliográficos
Autores principales: Cella, Chiara Alessandra, Cazzoli, Riccardo, Fazio, Nicola, De Petro, Giuseppina, Gaudenzi, Germano, Carra, Silvia, Romanenghi, Mauro, Spada, Francesca, Grossi, Ilaria, Pallavicini, Isabella, Minucci, Saverio, Vitale, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644769/
https://www.ncbi.nlm.nih.gov/pubmed/37855330
http://dx.doi.org/10.1530/ERC-23-0232