Pathogenic Germline Variants in BRCA1/2 and p53 Identified by Real-world Comprehensive Cancer Genome Profiling Tests in Asian Patients

Cancer genome profiling (CGP) occasionally identifies pathogenic germline variants (PGV) in cancer susceptibility genes (CSG) as secondary findings. Here, we analyzed the prevalence and clinical characteristics of PGVs based on nationwide real-world data from CGP tests in Japan. We analyzed the geno...

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Detalles Bibliográficos
Autores principales: Satake, Tomoyuki, Kondo, Shunsuke, Tanabe, Noriko, Mizuno, Takaaki, Katsuya, Yuki, Sato, Jun, Koyama, Takafumi, Yoshida, Tatsuya, Hirata, Makoto, Yamamoto, Noboru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644847/
https://www.ncbi.nlm.nih.gov/pubmed/37916805
http://dx.doi.org/10.1158/2767-9764.CRC-23-0018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644847/
https://www.ncbi.nlm.nih.gov/pubmed/37916805
http://dx.doi.org/10.1158/2767-9764.CRC-23-0018

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