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Utility of dansyl chloride for the establishment of a sensitive spectrofluorimetric approach for estimating midodrine hydrochloride: application to content uniformity testing

A new, straightforward spectrofluorimetric approach with high sensitivity was established for determining midodrine hydrochloride based on derivatizing this drug through its reaction with 5-(dimethylamino)naphthalene-1-sulfonyl chloride (dansyl chloride). The highly fluorescent product was extracted...

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Detalles Bibliográficos
Autores principales: Derayea, Sayed M., Abdelgaleel, Mahmoud, Nagi, Dalia M., Oraby, Mohamed, Khashaba, Pakinaz Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644863/
https://www.ncbi.nlm.nih.gov/pubmed/38025857
http://dx.doi.org/10.1039/d3ra06268f