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A semi-automated microscopic image analysis method for scoring Ki-67 nuclear immunostaining

Nuclear proliferation marker MIB-1 (Ki-67) immunohistochemistry (IHC) is used to examine tumor cell proliferation. However, the diagnostic or prognostic value of the Ki-67 nuclear staining intensity and location, defined as nuclear gradient (NG), has not been assessed. This study examined the potent...

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Detalles Bibliográficos
Autores principales: Fernezlian, S.M., Baldavira, C.M., de Souza, M.L.F., Farhat, C., de Vilhena, A.F., Pereira, J.C.N., de Campos, J.R.M., Takagaki, T., Balancin, M.L., Ab'Saber, A.M., Capelozzi, V.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644968/
https://www.ncbi.nlm.nih.gov/pubmed/37970922
http://dx.doi.org/10.1590/1414-431X2023e12922