Insulin receptor Arg717 and IGF-1 receptor Arg704 play a key role in ligand binding and in receptor activation

The insulin receptor (IR, with its isoforms IR-A and IR-B) and the insulin-like growth factor 1 receptor (IGF-1R) are related tyrosine kinase receptors. Recently, the portfolio of solved hormone–receptor structures has grown extensively thanks to advancements in cryo-electron microscopy. However, th...

Descripción completa

Detalles Bibliográficos
Autores principales: Kertisová, Anna, Žáková, Lenka, Macháčková, Kateřina, Marek, Aleš, Šácha, Pavel, Pompach, Petr, Jiráček, Jiří, Selicharová, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645074/
https://www.ncbi.nlm.nih.gov/pubmed/37935358
http://dx.doi.org/10.1098/rsob.230142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645074/
https://www.ncbi.nlm.nih.gov/pubmed/37935358
http://dx.doi.org/10.1098/rsob.230142

Ejemplares similares