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Guiding the design of well-powered Hi-C experiments to detect differential loops
MOTIVATION: Three-dimensional chromatin structure plays an important role in gene regulation by connecting regulatory regions and gene promoters. The ability to detect the formation and loss of these loops in various cell types and conditions provides valuable information on the mechanisms driving t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645293/ https://www.ncbi.nlm.nih.gov/pubmed/38023330 http://dx.doi.org/10.1093/bioadv/vbad152 |