Deletions of singular U1 snRNA gene significantly interfere with transcription and 3’-end mRNA formation

Small nuclear RNAs (snRNAs) are structural and functional cores of the spliceosome. In metazoan genomes, each snRNA has multiple copies/variants, up to hundreds in mammals. However, the expressions and functions of each copy/variant in one organism have not been systematically studied. Focus on U1 s...

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Detalles Bibliográficos
Autores principales: Wang, Mei, Liang, An-Min, Zhou, Zhen-Zhen, Pang, Ting-Lin, Fan, Yu-Jie, Xu, Yong-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645366/
https://www.ncbi.nlm.nih.gov/pubmed/37917726
http://dx.doi.org/10.1371/journal.pgen.1011021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645366/
https://www.ncbi.nlm.nih.gov/pubmed/37917726
http://dx.doi.org/10.1371/journal.pgen.1011021

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