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Deletions of singular U1 snRNA gene significantly interfere with transcription and 3’-end mRNA formation
Small nuclear RNAs (snRNAs) are structural and functional cores of the spliceosome. In metazoan genomes, each snRNA has multiple copies/variants, up to hundreds in mammals. However, the expressions and functions of each copy/variant in one organism have not been systematically studied. Focus on U1 s...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645366/ https://www.ncbi.nlm.nih.gov/pubmed/37917726 http://dx.doi.org/10.1371/journal.pgen.1011021 |