Population-level single-cell genomics reveals conserved gene programs in systemic juvenile idiopathic arthritis

Systemic autoimmune and autoinflammatory diseases are characterized by genetic and cellular heterogeneity. While current single-cell genomics methods provide insights into known disease subtypes, these analysis methods do not readily reveal novel cell-type perturbation programs shared among distinct...

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Detalles Bibliográficos
Autores principales: Verweyen, Emely L., Thakkar, Kairavee, Dhakal, Sanjeev, Baker, Elizabeth, Chetal, Kashish, Schnell, Daniel, Canna, Scott, Grom, Alexei A., Salomonis, Nathan, Schulert, Grant S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645394/
https://www.ncbi.nlm.nih.gov/pubmed/37733441
http://dx.doi.org/10.1172/JCI166741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645394/
https://www.ncbi.nlm.nih.gov/pubmed/37733441
http://dx.doi.org/10.1172/JCI166741

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