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Population-level single-cell genomics reveals conserved gene programs in systemic juvenile idiopathic arthritis
Systemic autoimmune and autoinflammatory diseases are characterized by genetic and cellular heterogeneity. While current single-cell genomics methods provide insights into known disease subtypes, these analysis methods do not readily reveal novel cell-type perturbation programs shared among distinct...
Autores principales: | Verweyen, Emely L., Thakkar, Kairavee, Dhakal, Sanjeev, Baker, Elizabeth, Chetal, Kashish, Schnell, Daniel, Canna, Scott, Grom, Alexei A., Salomonis, Nathan, Schulert, Grant S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645394/ https://www.ncbi.nlm.nih.gov/pubmed/37733441 http://dx.doi.org/10.1172/JCI166741 |
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