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Astrocyte and L-lactate in the anterior cingulate cortex modulate schema memory and neuronal mitochondrial biogenesis

Astrocyte-derived L-lactate was shown to confer beneficial effects on synaptic plasticity and cognitive functions. However, how astrocytic G(i) signaling in the anterior cingulate cortex (ACC) modulates L-lactate levels and schema memory is not clear. Here, using chemogenetic approach and well-estab...

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Detalles Bibliográficos
Autores principales: Akter, Mastura, Hasan, Mahadi, Ramkrishnan, Aruna Surendran, Iqbal, Zafar, Zheng, Xianlin, Fu, Zhongqi, Lei, Zhuogui, Karim, Anwarul, Li, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645423/
https://www.ncbi.nlm.nih.gov/pubmed/37960975
http://dx.doi.org/10.7554/eLife.85751