Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors

In vitro culture systems that structurally model human myogenesis and promote PAX7(+) myogenic progenitor maturation have not been established. Here we report that human skeletal muscle organoids can be differentiated from induced pluripotent stem cell lines to contain paraxial mesoderm and neuromes...

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Detalles Bibliográficos
Autores principales: Mavrommatis, Lampros, Jeong, Hyun-Woo, Kindler, Urs, Gomez-Giro, Gemma, Kienitz, Marie-Cecile, Stehling, Martin, Psathaki, Olympia E, Zeuschner, Dagmar, Bixel, M Gabriele, Han, Dong, Morosan-Puopolo, Gabriela, Gerovska, Daniela, Yang, Ji Hun, Kim, Jeong Beom, Arauzo-Bravo, Marcos J, Schwamborn, Jens C, Hahn, Stephan A, Adams, Ralf H, Schöler, Hans R, Vorgerd, Matthias, Brand-Saberi, Beate, Zaehres, Holm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645425/
https://www.ncbi.nlm.nih.gov/pubmed/37963071
http://dx.doi.org/10.7554/eLife.87081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645425/
https://www.ncbi.nlm.nih.gov/pubmed/37963071
http://dx.doi.org/10.7554/eLife.87081

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