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A systems-level analysis of the mutually antagonistic roles of RKIP and BACH1 in dynamics of cancer cell plasticity

Epithelial–mesenchymal transition (EMT) is an important axis of phenotypic plasticity—a hallmark of cancer metastasis. Raf kinase-B inhibitor protein (RKIP) and BTB and CNC homology 1 (BACH1) are reported to influence EMT. In breast cancer, they act antagonistically, but the exact nature of their ro...

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Detalles Bibliográficos
Autores principales: Shyam, Sai, Ramu, Soundharya, Sehgal, Manas, Jolly, Mohit Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645512/
https://www.ncbi.nlm.nih.gov/pubmed/37963558
http://dx.doi.org/10.1098/rsif.2023.0389