Power of inclusion: Enhancing polygenic prediction with admixed individuals

Admixed individuals offer unique opportunities for addressing limited transferability in polygenic scores (PGSs), given the substantial trans-ancestry genetic correlation in many complex traits. However, they are rarely considered in PGS training, given the challenges in representing ancestry-matche...

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Detalles Bibliográficos
Autores principales: Tanigawa, Yosuke, Kellis, Manolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645553/
https://www.ncbi.nlm.nih.gov/pubmed/37890495
http://dx.doi.org/10.1016/j.ajhg.2023.09.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645553/
https://www.ncbi.nlm.nih.gov/pubmed/37890495
http://dx.doi.org/10.1016/j.ajhg.2023.09.013

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