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Power of inclusion: Enhancing polygenic prediction with admixed individuals
Admixed individuals offer unique opportunities for addressing limited transferability in polygenic scores (PGSs), given the substantial trans-ancestry genetic correlation in many complex traits. However, they are rarely considered in PGS training, given the challenges in representing ancestry-matche...
Autores principales: | Tanigawa, Yosuke, Kellis, Manolis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645553/ https://www.ncbi.nlm.nih.gov/pubmed/37890495 http://dx.doi.org/10.1016/j.ajhg.2023.09.013 |
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