LAMC2 promotes EGFR cell membrane localization and acts as a novel biomarker for tyrosine kinase inhibitors (TKIs) sensitivity in lung cancer

The epidermal growth factor receptor (EGFR) is one of the first and most prominent driver genes known to promote malignant lung cancer. Investigating regulatory mechanisms beyond ligand-receptor binding, phosphorylation, and receptor kinase activation as means of EGFR signaling activation is importa...

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Detalles Bibliográficos
Autores principales: Tong, Dongdong, Wang, Xiaofei, Liu, Liying, Wen, Ting, Chen, QiaoYi, Huang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645587/
https://www.ncbi.nlm.nih.gov/pubmed/37542131
http://dx.doi.org/10.1038/s41417-023-00654-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645587/
https://www.ncbi.nlm.nih.gov/pubmed/37542131
http://dx.doi.org/10.1038/s41417-023-00654-7

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