B-type Plexins promote the GTPase activity of Ran to affect androgen receptor nuclear translocation in prostate cancer

Resistance to anti-androgen therapy for metastatic prostate cancer is a major clinical problem. Sema3C promotes resistance to androgen withdrawal via its receptor, PlexinB1. Activation of PlexinB1 promotes the ligand-independent nuclear translocation of the androgen receptor (AR), which may contribu...

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Detalles Bibliográficos
Autores principales: Garg, Ritu, Endzhievskaya, Sofia, Williamson, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645588/
https://www.ncbi.nlm.nih.gov/pubmed/37563360
http://dx.doi.org/10.1038/s41417-023-00655-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645588/
https://www.ncbi.nlm.nih.gov/pubmed/37563360
http://dx.doi.org/10.1038/s41417-023-00655-6

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