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Targeting SOD1 via RNAi with PEGylated graphene oxide nanoparticles in platinum-resistant ovarian cancer

Acquired platinum resistance poses a significant therapeutic impediment to ovarian cancer patient care, accounting for more than 200,000 deaths annually worldwide. We previously identified that overexpression of the antioxidant superoxide dismutase 1 (SOD1) in ovarian cancer is associated with a pla...

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Detalles Bibliográficos
Autores principales: Szénási, Attila, Sivasudhan, Enakshi, Du, Hong, Zhang, Peizhuo, Huang, Jie, Zhang, Zhijun, Rocha, Sonia, Wang, Mu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645591/
https://www.ncbi.nlm.nih.gov/pubmed/37582934
http://dx.doi.org/10.1038/s41417-023-00659-2