scDiffCom: a tool for differential analysis of cell–cell interactions provides a mouse atlas of aging changes in intercellular communication

Dysregulation of intercellular communication is a hallmark of aging. To better quantify and explore changes in intercellular communication, we present scDiffCom and scAgeCom. scDiffCom is an R package, relying on approximately 5,000 curated ligand–receptor interactions, that performs differential in...

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Detalles Bibliográficos
Autores principales: Lagger, Cyril, Ursu, Eugen, Equey, Anaïs, Avelar, Roberto A., Pisco, Angela Oliveira, Tacutu, Robi, de Magalhães, João Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645595/
https://www.ncbi.nlm.nih.gov/pubmed/37919434
http://dx.doi.org/10.1038/s43587-023-00514-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645595/
https://www.ncbi.nlm.nih.gov/pubmed/37919434
http://dx.doi.org/10.1038/s43587-023-00514-x

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