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CD133(+) endothelial-like stem cells restore neovascularization and promote longevity in progeroid and naturally aged mice

The stem cell theory of aging dictates that a decline in the number and/or function of stem cells causes tissue degeneration and aging; however, it still lacks unequivocal experimental support. Here, using lineage tracing and single-cell transcriptomics, we identify a population of CD133(+) bone mar...

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Detalles Bibliográficos
Autores principales: Sun, Shimin, Meng, Yuan, Li, Mingying, Tang, Xiaolong, Hu, Wenjing, Wu, Weiwei, Li, Guo, Pang, Qiuxiang, Wang, Wengong, Liu, Baohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645602/
https://www.ncbi.nlm.nih.gov/pubmed/37946040
http://dx.doi.org/10.1038/s43587-023-00512-z