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Feasibility of mass cytometry proteomic characterisation of circulating tumour cells in head and neck squamous cell carcinoma for deep phenotyping

BACKGROUND: Circulating tumour cells (CTCs) are a potential cancer biomarker, but current methods of CTC analysis at single-cell resolution are limited. Here, we describe high-dimensional single-cell mass cytometry proteomic analysis of CTCs in HNSCC. METHODS: Parsortix microfluidic-enriched CTCs fr...

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Detalles Bibliográficos
Autores principales: Payne, Karl, Brooks, Jill, Batis, Nikolaos, Khan, Naeem, El-Asrag, Mohammed, Nankivell, Paul, Mehanna, Hisham, Taylor, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645808/
https://www.ncbi.nlm.nih.gov/pubmed/37735243
http://dx.doi.org/10.1038/s41416-023-02428-2