CHEX-seq detects single-cell genomic single-stranded DNA with catalytical potential

Genomic DNA (gDNA) undergoes structural interconversion between single- and double-stranded states during transcription, DNA repair and replication, which is critical for cellular homeostasis. We describe “CHEX-seq” which identifies the single-stranded DNA (ssDNA) in situ in individual cells. CHEX-s...

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Detalles Bibliográficos
Autores principales: Lu, Youtao, Lee, Jaehee, Li, Jifen, Allu, Srinivasa Rao, Wang, Jinhui, Kim, HyunBum, Bullaughey, Kevin L., Fisher, Stephen A., Nordgren, C. Erik, Rosario, Jean G., Anderson, Stewart A., Ulyanova, Alexandra V., Brem, Steven, Chen, H. Isaac, Wolf, John A., Grady, M. Sean, Vinogradov, Sergei A., Kim, Junhyong, Eberwine, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645931/
https://www.ncbi.nlm.nih.gov/pubmed/37963886
http://dx.doi.org/10.1038/s41467-023-43158-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645931/
https://www.ncbi.nlm.nih.gov/pubmed/37963886
http://dx.doi.org/10.1038/s41467-023-43158-6

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