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Functional annotation of enzyme-encoding genes using deep learning with transformer layers

Functional annotation of open reading frames in microbial genomes remains substantially incomplete. Enzymes constitute the most prevalent functional gene class in microbial genomes and can be described by their specific catalytic functions using the Enzyme Commission (EC) number. Consequently, the a...

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Detalles Bibliográficos
Autores principales: Kim, Gi Bae, Kim, Ji Yeon, Lee, Jong An, Norsigian, Charles J., Palsson, Bernhard O., Lee, Sang Yup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645960/
https://www.ncbi.nlm.nih.gov/pubmed/37963869
http://dx.doi.org/10.1038/s41467-023-43216-z