SETD5 regulates the OGT-catalyzed O-GlcNAcylation of RNA polymerase II, which is involved in the stemness of colorectal cancer cells

The dosage-dependent recruitment of RNA polymerase II (Pol II) at the promoters of genes related to neurodevelopment and stem cell maintenance is required for transcription by the fine-tuned expression of SET-domain-containing protein 5 (SETD5). Pol II O-GlcNAcylation by O-GlcNAc transferase (OGT) i...

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Detalles Bibliográficos
Autores principales: Cho, Hye In, Jo, Sora, Kim, Min Seong, Kim, Han Byeol, Liu, Xingzhe, Xuan, Yanhua, Cho, Jin Won, Jang, Yeun Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646014/
https://www.ncbi.nlm.nih.gov/pubmed/37963940
http://dx.doi.org/10.1038/s41598-023-46923-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646014/
https://www.ncbi.nlm.nih.gov/pubmed/37963940
http://dx.doi.org/10.1038/s41598-023-46923-1

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