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The EZH2-H3K27me3 axis modulates aberrant transcription and apoptosis in cyclophosphamide-induced ovarian granulosa cell injury

Chemotherapy-induced ovarian damage and infertility are significant concerns for women of childbearing age with cancer; however, the underlying mechanisms are still not fully understood. Our study has revealed a close association between epigenetic regulation and cyclophosphamide (CTX)-induced ovari...

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Detalles Bibliográficos
Autores principales: Chen, Yingyan, Ai, Leilei, Zhang, Yingyi, Li, Xiang, Xu, Shiqian, Yang, Weijie, Jin, Jiamin, Ma, Yerong, Hu, Zhanhong, Zhang, Yinli, Rong, Yan, Zhang, Songying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646043/
https://www.ncbi.nlm.nih.gov/pubmed/37963880
http://dx.doi.org/10.1038/s41420-023-01705-6