LASS2 enhances p53 protein stability and nuclear import to suppress liver cancer progression through interaction with MDM2/MDMX

LASS2 functions as a tumor suppressor in hepatocellular carcinoma (HCC), the most common type of primary liver cancer, but the underlying mechanism of its action remains largely unknown. Moreover, details on its role and the downstream mechanisms in Cholangiocarcinoma (CCA) and hepatoblastoma (HB),...

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Detalles Bibliográficos
Autores principales: Zhao, Qingqing, He, Wei, Liu, Zhouheng, Huang, Liangliang, Yang, Xiaoli, Liu, Yong, Chen, Rui, Min, Xun, Yang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646090/
https://www.ncbi.nlm.nih.gov/pubmed/37963859
http://dx.doi.org/10.1038/s41420-023-01709-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646090/
https://www.ncbi.nlm.nih.gov/pubmed/37963859
http://dx.doi.org/10.1038/s41420-023-01709-2

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