Inhibition of Hedgehog signaling ameliorates foam cell formation by promoting autophagy in early atherosclerosis

Macrophages are the origin of most foam cells in the early stage of atherosclerotic plaques. However, the mechanism involved in the formation of macrophage-derived foam cell formation remains unclear. Here, we revealed that the hedgehog (Hh) signaling is critical in autophagy-lysosome pathway regula...

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Detalles Bibliográficos
Autores principales: Zhang, Yuting, Xin, Weijuan, Hu, Xiaozhi, Wang, Hanqi, Ye, Xiaomiao, Xu, Caili, Nan, Yanyang, Wu, Zhengyu, Ju, Dianwen, Fan, Jiajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646116/
https://www.ncbi.nlm.nih.gov/pubmed/37963874
http://dx.doi.org/10.1038/s41419-023-06270-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646116/
https://www.ncbi.nlm.nih.gov/pubmed/37963874
http://dx.doi.org/10.1038/s41419-023-06270-5

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