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Differential response of HER2-positive breast cancer to anti-HER2 therapy based on HER2 protein expression level

BACKGROUND: Increasing data indicate that HER2-positive (HER2 + ) breast cancer (BC) subtypes exhibit differential responses to targeted anti-HER2 therapy. This study aims to investigate these differences and the potential underlying molecular mechanisms. METHODS: A large cohort of BC patients (n = ...

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Detalles Bibliográficos
Autores principales: Atallah, N. M., Alsaleem, M., Toss, M. S., Mongan, N. P., Rakha, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646129/
https://www.ncbi.nlm.nih.gov/pubmed/37740038
http://dx.doi.org/10.1038/s41416-023-02426-4