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In the skin lesions of patients with mycosis fungoides, the number of MRGPRX2-expressing cells is increased and correlates with mast cell numbers

BACKGROUND: Mycosis fungoides (MF) is an indolent T-cell lymphoma that mainly affects the skin and presents with itch in more than half of the patients. Recently, the expression of Mas-related G protein-coupled receptor X2 (MRGPRX2), a receptor of mast cell (MC) responsible for the IgE-independent n...

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Detalles Bibliográficos
Autores principales: Hu, Man, Pyatilova, Polina, Altrichter, Sabine, Sheng, Caibin, Liu, Nian, Terhorst-Molawi, Dorothea, Lohse, Katharina, Ginter, Katharina, Puhl, Viktoria, Maurer, Marcus, Metz, Martin, Kolkhir, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646224/
https://www.ncbi.nlm.nih.gov/pubmed/38022672
http://dx.doi.org/10.3389/fimmu.2023.1197821