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Product Profiles of Promiscuous Enzymes Can be Altered by Controlling In Vivo Spatial Organization

Enzyme spatial organization is an evolved mechanism for facilitating multi‐step biocatalysis and can play an important role in the regulation of promiscuous enzymes. The latter function suggests that artificial spatial organization can be an untapped avenue for controlling the specificity of bioengi...

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Detalles Bibliográficos
Autores principales: Cheah, Li Chen, Liu, Lian, Plan, Manuel R., Peng, Bingyin, Lu, Zeyu, Schenk, Gerhard, Vickers, Claudia E., Sainsbury, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646250/
https://www.ncbi.nlm.nih.gov/pubmed/37750486
http://dx.doi.org/10.1002/advs.202303415