Cargando…

In Vivo Intra‐Uterine Delivery of TAT‐Fused Cre Recombinase and CRISPR/Cas9 Editing System in Mice Unveil Histopathology of Pten/p53‐Deficient Endometrial Cancers

Phosphatase and TENsin homolog (Pten) and p53 are two of the most frequently mutated tumor suppressor genes in endometrial cancer. However, the functional consequences and histopathological manifestation of concomitant p53 and Pten loss of function alterations in the development of endometrial cance...

Descripción completa

Detalles Bibliográficos
Autores principales: Navaridas, Raúl, Vidal‐Sabanés, Maria, Ruiz‐Mitjana, Anna, Altés, Gisela, Perramon‐Güell, Aida, Yeramian, Andree, Egea, Joaquim, Encinas, Mario, Gatius, Sonia, Matias‐Guiu, Xavier, Dolcet, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646277/
https://www.ncbi.nlm.nih.gov/pubmed/37749866
http://dx.doi.org/10.1002/advs.202303134