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In Vivo Intra‐Uterine Delivery of TAT‐Fused Cre Recombinase and CRISPR/Cas9 Editing System in Mice Unveil Histopathology of Pten/p53‐Deficient Endometrial Cancers
Phosphatase and TENsin homolog (Pten) and p53 are two of the most frequently mutated tumor suppressor genes in endometrial cancer. However, the functional consequences and histopathological manifestation of concomitant p53 and Pten loss of function alterations in the development of endometrial cance...
Autores principales: | Navaridas, Raúl, Vidal‐Sabanés, Maria, Ruiz‐Mitjana, Anna, Altés, Gisela, Perramon‐Güell, Aida, Yeramian, Andree, Egea, Joaquim, Encinas, Mario, Gatius, Sonia, Matias‐Guiu, Xavier, Dolcet, Xavier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646277/ https://www.ncbi.nlm.nih.gov/pubmed/37749866 http://dx.doi.org/10.1002/advs.202303134 |
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