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Early Progression of Abdominal Aortic Aneurysm is Decelerated by Improved Endothelial Barrier Function via ALDH2‐LIN28B‐ELK3 Signaling

The involvement of endothelial barrier function in abdominal aortic aneurysm (AAA) and its upstream regulators remains unknown. Single‐cell RNA sequencing shows that disrupted endothelial focal junction is an early (3 days) and persistent (28 days) event during Angiotensin II (Ang II)‐induced AAA pr...

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Detalles Bibliográficos
Autores principales: Yang, Kehui, Cui, Sumei, Wang, Jingwen, Xu, Tonghui, Du, Han, Yue, Hongwei, Ye, Huaqing, Guo, Jialin, Zhang, Jian, Li, Pengpai, Guo, Yunyun, Pan, Chang, Pang, Jiaojiao, Wang, Jiali, Yu, Xiao, Zhang, Cheng, Liu, Zhiping, Chen, Yuguo, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646281/
https://www.ncbi.nlm.nih.gov/pubmed/37822152
http://dx.doi.org/10.1002/advs.202302231