Semaphorin 7a aggravates TGF-β1-induced airway EMT through the FAK/ERK1/2 signaling pathway in asthma

BACKGROUND: TGF-β1 can induce epithelial-mesenchymal transition (EMT) in primary airway epithelial cells (AECs). Semaphorin7A (Sema7a) plays a crucial role in regulating immune responses and initiating and maintaining transforming growth factor β1 TGF-β1-induced fibrosis. OBJECTIVE: To determine the...

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Detalles Bibliográficos
Autores principales: Peng, Haiying, Sun, Fei, Jiang, Yunxiu, Guo, Zihan, Liu, Xinyi, Zuo, Anli, Lu, Degan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646317/
https://www.ncbi.nlm.nih.gov/pubmed/38022556
http://dx.doi.org/10.3389/fimmu.2023.1167605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646317/
https://www.ncbi.nlm.nih.gov/pubmed/38022556
http://dx.doi.org/10.3389/fimmu.2023.1167605

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