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Semaphorin 7a aggravates TGF-β1-induced airway EMT through the FAK/ERK1/2 signaling pathway in asthma
BACKGROUND: TGF-β1 can induce epithelial-mesenchymal transition (EMT) in primary airway epithelial cells (AECs). Semaphorin7A (Sema7a) plays a crucial role in regulating immune responses and initiating and maintaining transforming growth factor β1 TGF-β1-induced fibrosis. OBJECTIVE: To determine the...
Autores principales: | Peng, Haiying, Sun, Fei, Jiang, Yunxiu, Guo, Zihan, Liu, Xinyi, Zuo, Anli, Lu, Degan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646317/ https://www.ncbi.nlm.nih.gov/pubmed/38022556 http://dx.doi.org/10.3389/fimmu.2023.1167605 |
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