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Exploring lncRNAs associated with human pancreatic islet cell death induced by transfer of adoptive lymphocytes in a humanized mouse model

BACKGROUND: Long noncoding RNA (lncRNA)-mediated posttranscriptional and epigenetic landscapes of gene regulation are associated with numerous human diseases. However, the regulatory mechanisms governing human β-cell function and survival remain unknown. Owing to technical and ethical constraints, s...

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Detalles Bibliográficos
Autores principales: Hossain, Md Munir, Roat, Regan, Christopherson, Jenica, Free, Colette, Ansarullah, James, Brian, Guo, Zhiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646418/
https://www.ncbi.nlm.nih.gov/pubmed/38027148
http://dx.doi.org/10.3389/fendo.2023.1244688