A Cell Surface-Binding Antibody Atlas Nominates a MUC18-Directed Antibody–Drug Conjugate for Targeting Melanoma

Recent advances in targeted therapy and immunotherapy have substantially improved the treatment of melanoma. However, therapeutic strategies are still needed for unresponsive or treatment-relapsed patients with melanoma. To discover antibody–drug conjugate (ADC)–tractable cell surface targets for me...

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Detalles Bibliográficos
Autores principales: Shi, Jing, Jiao, Tao, Guo, Qian, Weng, Weining, Ma, Linjie, Zhang, Qing, Wang, Lijun, Zhang, Jianjian, Chen, Caiwei, Huang, Yaling, Wang, Mingqiao, Pan, Rong, Tang, Yanfang, Hu, Wenhao, Meng, Tao, Liu, Shu-Hui, Guo, Jun, Kong, Yan, Meng, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Therapeutic Development and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646479/
https://www.ncbi.nlm.nih.gov/pubmed/37668527
http://dx.doi.org/10.1158/0008-5472.CAN-23-1356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646479/
https://www.ncbi.nlm.nih.gov/pubmed/37668527
http://dx.doi.org/10.1158/0008-5472.CAN-23-1356

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