cIAPs control RIPK1 kinase activity‐dependent and ‐independent cell death and tissue inflammation

Cellular inhibitor of apoptosis proteins (cIAPs) are RING‐containing E3 ubiquitin ligases that ubiquitylate receptor‐interacting protein kinase 1 (RIPK1) to regulate TNF signalling. Here, we established mice simultaneously expressing enzymatically inactive cIAP1/2 variants, bearing mutations in the...

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Detalles Bibliográficos
Autores principales: Schorn, Fabian, Werthenbach, J Paul, Hoffmann, Mattes, Daoud, Mila, Stachelscheid, Johanna, Schiffmann, Lars M, Hildebrandt, Ximena, Lyu, Su Ir, Peltzer, Nieves, Quaas, Alexander, Vucic, Domagoj, Silke, John, Pasparakis, Manolis, Kashkar, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646551/
https://www.ncbi.nlm.nih.gov/pubmed/37789765
http://dx.doi.org/10.15252/embj.2023113614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646551/
https://www.ncbi.nlm.nih.gov/pubmed/37789765
http://dx.doi.org/10.15252/embj.2023113614

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