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cIAPs control RIPK1 kinase activity‐dependent and ‐independent cell death and tissue inflammation

Cellular inhibitor of apoptosis proteins (cIAPs) are RING‐containing E3 ubiquitin ligases that ubiquitylate receptor‐interacting protein kinase 1 (RIPK1) to regulate TNF signalling. Here, we established mice simultaneously expressing enzymatically inactive cIAP1/2 variants, bearing mutations in the...

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Detalles Bibliográficos
Autores principales:	Schorn, Fabian, Werthenbach, J Paul, Hoffmann, Mattes, Daoud, Mila, Stachelscheid, Johanna, Schiffmann, Lars M, Hildebrandt, Ximena, Lyu, Su Ir, Peltzer, Nieves, Quaas, Alexander, Vucic, Domagoj, Silke, John, Pasparakis, Manolis, Kashkar, Hamid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646551/ https://www.ncbi.nlm.nih.gov/pubmed/37789765 http://dx.doi.org/10.15252/embj.2023113614

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