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Adolescents with obesity treated with exenatide maintain endogenous GLP-1, reduce DPP-4, and improve glycemic control

BACKGROUND: GLP-1 receptor agonists (GLP-1RA) are increasingly used to treat adolescent obesity. However, the effect on endogenous GLP-1 secretory patterns following treatment in adolescents is unknown. The GLP-1RA exenatide was shown to significantly lower BMI and 2-hour glucose in adolescents with...

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Detalles Bibliográficos
Autores principales: Stenlid, Rasmus, Cerenius, Sara Y., Wen, Quan, Aydin, Banu Küçükemre, Manell, Hannes, Chowdhury, Azazul, Kristinsson, Hjalti, Ciba, Iris, Gjessing, Erik S., Mörwald, Katharina, Gomahr, Julian, Heu, Verena, Weghuber, Daniel, Forslund, Anders, Bergsten, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646558/
https://www.ncbi.nlm.nih.gov/pubmed/38027106
http://dx.doi.org/10.3389/fendo.2023.1293093