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Effects of EGFR driver mutations on pathologic regression in resectable locally advanced non-small cell lung cancer treated with neoadjuvant chemoradiation and completion surgery

OBJECTIVE: We hypothesized that driver mutations in epidermal growth factor receptor (EGFR) are associated with decreased pathologic response to neoadjuvant chemoradiation (NA-ChRT) in locally advanced non-small cell lung cancer (LA-NSCLC). METHODS: Patients with Stage IIB-IIIA NSCLC treated with NA...

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Detalles Bibliográficos
Autores principales: Appel, Sarit, Bar, Jair, Saad, Akram, Marom, Edith Michelle, Urban, Damien, Onn, Amir, Gantz-Sorotsky, Hadas, Kremer, Ran Yosef, Ben-Nun, Alon, Perelman, Marina, Ofek, Efrat, Yacobi, Rinat, Daher, Sameh, Rasco, Adi, Symon, Zvi, Lawrence, Yaacov Richard, Goldstein, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646649/
https://www.ncbi.nlm.nih.gov/pubmed/37751214
http://dx.doi.org/10.1259/bjr.20220763