Sex-associated early-life viral innate immune response is transcriptionally associated with chromatin remodeling of type-I IFN-inducible genes

This study investigates sex-associated systemic innate immune differences by examining bone marrow-derived dendritic cells (BMDCs). BMDC grown from 7-day-old mice show enhanced type-I interferon (IFN) signaling in female compared to male BMDC. Upon respiratory syncytial virus (RSV) infection of 7-da...

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Detalles Bibliográficos
Autores principales: Malinczak, Carrie-Anne, Fonseca, Wendy, Mire, Mohamed M., Parolia, Abhijit, Chinnaiyan, Arul, Rasky, Andrew J., Morris, Susan, Yagi, Kazuma, Bermick, Jennifer R., Lukacs, Nicholas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646734/
https://www.ncbi.nlm.nih.gov/pubmed/37302711
http://dx.doi.org/10.1016/j.mucimm.2023.06.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646734/
https://www.ncbi.nlm.nih.gov/pubmed/37302711
http://dx.doi.org/10.1016/j.mucimm.2023.06.002

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