Oncogenic PIK3CA recruits myeloid‐derived suppressor cells to shape the immunosuppressive tumour microenvironment in luminal breast cancer through the 5‐lipoxygenase‐dependent arachidonic acid pathway

Background: Oncogenic PIK3CA mutations (PIK3CA(mut)) frequently occur in a higher proportion in luminal breast cancer (LBC), especially in refractory advanced cases, and are associated with changes in tumour cellular metabolism. Nevertheless, its effect on the progression of the immune microenvironm...

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Detalles Bibliográficos
Autores principales: Li, Xingchen, Chen, Guidong, Wang, Fanchen, Guo, Xiaojing, Zhang, Rui, Liu, Pengpeng, Dong, Li, Yu, Wenwen, Wang, Huan, Wang, Hailong, Yu, Jinpu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646754/
https://www.ncbi.nlm.nih.gov/pubmed/37965796
http://dx.doi.org/10.1002/ctm2.1483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646754/
https://www.ncbi.nlm.nih.gov/pubmed/37965796
http://dx.doi.org/10.1002/ctm2.1483

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